The girlfriend whispers to CIS is the first occurrence of neurological symptoms that lasts a minimum of 24 hours. My Dr suggested the process may be harder in the future and felt since we were in right after the FDA approval we may have gotten lucky. Call your doctor if you think youve taken too much Kesimpta. KESIMPTA taken before or after other medicines that weaken the immune system could increase your risk of getting infections. Your spinal cord contains neurons (nerve cells) that help your brain communicate with the rest of your body. Here is an interview of Yvonne where she talks about her show about being a virgin, her strict parents, her show Insecure and many more. Here are some frequently asked questions about the drugs side effects and their answers. Members receive In the same podcast, she also revealed that even after her break-up, she is happy not at all sitting around depressed, sad or crying. urinary tract infection (UTI) injection site reactions (reactions around the area of the Kesimpta injection)*. Serious side effects that have been reported and their symptoms include: * For more information about this side effect, see Side effect specifics below. It is not known if KESIMPTA will harm your unborn baby. after your last treatment. Here are planning and prepping tips to make mealtime easier. Arzerra (ofatumumab) injection, for intravenous use. Kesimpta is an anti-CD20 monoclonal antibody that's approved to treat relapsing types of MS. The actress in Nissan commercial is Brie Larson. More details can be found in our, How Multiple Sclerosis Affects the Black Community, Acute Disseminated Encephalomyelitis (ADEM), Myelin Oligodendrocyte Glycoprotein Antibody Disease (MOGAD), Neuromyelitis Optica Spectrum Disorder (NMOSD), New to Pediatric MS: Navigating Your Journey, Make the Most of Your Healthcare Provider Visits, aHSCT in MS (Autologous Hematopoietic Stem Cell Transplantation), Cumbre de Esclerosis Mltiple para Hispanos/Latinx, Resilience: Addressing the Challenges of MS, Edward M. Dowd Personal Advocate Program, Emotional Well-Being and Multiple Sclerosis, Multiple Sclerosis and the Americans with Disabilities Act (ADA), COVID-19 Studies Recruiting People with MS, Research Studies: Newly Diagnosed with MS, Independent Review of Society's Research Programs, Diversity, Equity and Inclusion and the National MS Society, Scientific Peer Reviewers & Advisory Committees, COVID-19 Information for Healthcare Providers, COVID-19 Vaccine Guidance for People Living with MS, Timing MS Medications with COVID-19 Vaccines, COVID-19 Vaccines for Children and Adolescents with MS and Related Disorders, Disease Modifying Therapy Guidance During COVID-19, Download the Medication Guide for patients, Read more about disease-modifying therapies and other treatments for MS and MS symptoms, The U.S. Food and Drug Administration has approved Kesimpta, The approval was based on two identical phase 3 studies (ACLEPIOS I and II) in which participants were randomly assigned to receive Kesimpta (self-injected once a month), or daily oral Aubagio. Before you start Kesimpta, you will have a blood test to check for an active or past hepatitis B virus (HBV) infection. Advertising Cookies: Before starting KESIMPTA, you'll get a blood test for hepatitis B virus (HBV). (For details on the drugs uses, see What is Kesimpta used to treat? above.). Research suggests vitamin C and B7 may worsen MS symptoms. Jason Alexander as Colonel Sanders. This is what causes many of the symptoms related to MS, such as: How Kesimpta treats MS isnt completely known. could increase your risk of getting infections. When this protective covering is damaged, your brain has trouble communicating with the rest of your body. Yvonne was dating Emmanuel Acho who is a former American football linebacker played in the National Football League (NFL) and is currently working as an analyst for ESPN. Copyright 2023 Multiple Sclerosis Association ofAmerica. She will be leading in the movie Spontaneous along with Katherine Langford, Charlie Plummer, Hayley Law, Piper Perabo, and Rob Huebel. Hair loss was not reported as a side effect of Kesimpta in clinical trials of the drug. Results of the ASCLEPIOS I and II studies found that Kesimpta demonstrated a significant reduction in ARR, the studies primary endpoint, by 51% and 59% (respectively) compared with Aubagio. Be sure to discuss the best treatment option for you with your doctor or pharmacist. St. Ives . If you develop serious side effects during Kesimpta treatment, call your doctor right away. The cause of RMS is unknown, and multiple factors are still being studied. Serious infections may occur during Kesimpta treatment. Symptoms range from numbness and tingling to blindness and paralysis, and there is currently no cure for MS. In addition to the 40-plus AT&T ads she's. See complete Terms & Conditions at start.kesimpta.com. For details about your risk of infections with Kesimpta, see Infections just above. progressive multifocal leukoencephalopathy (PML). Aubagio is a prescription drug used to treat MS and CIS. All rights reserved. Although it's not known exactly how KESIMPTA works in relapsing MS, it's thought to travel specifically to the lymph nodes based on the way it's taken. The article talks about 12 Rosario Dawson is a 41-year-old actress and producer, born on May 9th, 1979 . This dose is the higher of the two approved doses of Aubagio. By accepting, you consent to the use of all cookies and by declining, only essential cookies will be used to make our website work. Just administered this morning. and become a member if you have a prescription but aren't enrolled yet. She has three other siblings, all brothers and two of them are twins. Symptoms of low immunoglobulins can include: Before starting Kesimpta, talk with your doctor about any current or chronic (long-term) infections you have. Your spinal cord contains neurons (nerve cells) that help your brain communicate with the rest of your body. Its not known from studies of Kesimpta how often allergic reactions occur. So not feeling great when starting. There were no cases of PML in clinical trials of Kesimpta. 2 talking about this. KESIMPTA is a prescribed medical injection which is intended to treat those who suffer from relapsing forms of multiple sclerosis when administered regularly as ordered. Serious side effects from Kesimpta can occur, but they arent common. You should always consult your doctor or another healthcare professional before taking any medication. Kesimpta needs to be stored in the refrigerator between 2-8C. Will my MS symptoms come back after I stop using Kesimpta? Injection site reactions occur near the area of the injection. PML is a rare, serious brain infection caused by a virus that may get worse over Your doctor may start by prescribing loading doses of Kesimpta for you. You shouldn't take KESIMPTA if you have an active hepatitis B virus (HBV) infection. For a general overview of Kesimpta, see this article. This list doesnt include all possible mild side effects of the drug. This newly approved medication targets CD20, a protein found on the surface of B cells, which are immune system cells believed to contribute to the development of MS. Clinical Trials Theyll also suggest that you avoid live vaccines while using the drug and for a while after your last dose. And they can advise which form of Kesimpta is best for you. Your doctor will recommend the dosage of Kesimpta thats right for you. During the course of 12 months, 47% of individuals receiving Kesimpta and 24.5% of those taking Aubagio achieved NEDA-3. If you have more questions about how Kesimpta works, talk with your doctor or pharmacist. If they recommend that you start Kesimpta despite the positive test result, they may monitor your liver function on a routine basis. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Best food forward: Are algae the future of sustainable nutrition? Get in touch at 1-855-KESIMPTA (1-855-537-4678), 8:30 AM -8:00 PM ET, Monday-Friday. KESIMPTA taken before or after other medicines that weaken the immune system may increase your risk of getting infections. Dont take more Kesimpta than your doctor prescribes. The manufacturer of this drug doesnt provide reviews from people whove taken its drug. AUBAGIO is a registered trademark of Genzyme, a Sanofi company. Read on to learn about potential common, mild, and serious side effects. It auto-injects the medication when you click a button. Are breastfeeding or plan to breastfeed. She has made guest appearances in a number of television shows. The most obvious difference between the newly approved Kesimpta and the previously approved B-cell therapy Ocrevus (ocrelizumab), is the route of delivery. It's too early to assume the ramp down of symptoms is influenced by Kesimpta but I'd like to think it is at least contributing. Symptoms of HBV include abdominal pain, diarrhea, and jaundice. They can discuss the risks and benefits of breastfeeding during Kesimpta treatment. after treatment with KESIMPTA. Homeless people have been living . If you have ever had HBV infection, it may become active again during or after treatment with KESIMPTA (reactivation). These reactions were common in clinical trials of Kesimpta. It is caused by inflammation or loss of myelin, which protects the nerves in the central She also has guest starred on Everybody Hates Chris, Community, Gigantic, Glee, Switched at Birth, Girl Meets World and Supernatural. Regardless of which treatment is selected, we are always pleased to see a new option added to our ever-expanding variety of effective disease-modifying therapies aimed at slowing MS disease activity and preserving function.. Yesinjection demonstrations are available. MNT is the registered trade mark of Healthline Media. I would like to share my experience and hope it is helpful. Kesimpta contains the drug ofatumumab, which is a biologic medication. Does KESIMPTA have a patient assistance or support program? Hopefully, some of these women will be featured in the best Super Bowl commercials. Kesimpta comes in a box containing a pre-filled pen which contains 20 mg ofatumumab solution for injection (0.4 mL of 50 mg/mL solution). If you don't have an FDA-cleared sharps container, demo video. If youre a male taking Kesimpta, talk with your doctor about your birth control options. What Vitamins Should You Avoid if You Have MS? If you develop a side effect during Kesimpta treatment and want to tell the FDA about it, visit MedWatch. You are encouraged to report negative side effects of prescription drugs to the FDA. The usual dosage of Kesimpta is one injection into your lower belly, your upper arm, or the front of your thigh. The TV commercial promoting the medicine features. If youre able to become pregnant, your doctor will recommend using effective birth control during Kesimpta treatment and for at least 6 months after your last dose of Kesimpta. Injecting KESIMPTA can cause injection-related reactions that can happen within 24 hours (1 day) following To help prevent pregnancy, females* should use an effective form of birth control while taking Kesimpta. But your risk of these reactions is highest after you receive your first injection of the drug. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Weakened immune system. Fierce Pharma AsiaEisai's Alzheimer's trial deaths; Moderna's first M&A deal; GSK, WuXi's bispecific pact. If this happens, it may cause serious liver problems including liver failure or death. What is relapsing-remitting multiple sclerosis (RRMS)? Other serious side effects include injection-related reactions near the injection site (such as redness, swelling, itching, or pain) and other injection reactions such as fever, headache, pain in the muscles, chills, and tiredness. Update: The actress, Monica Ruiz, is alive and well. The actress in the Kesimpta commercial is Kami Dimitrova. Low immunoglobulins. But in a person with a weakened immune system, including someone using Kesimpta, a live vaccine could cause infection. Non-live vaccines dont contain any live bacteria or viruses. Your HCP will do blood tests to check your blood immunoglobulin levels. Your doctor or pharmacist can tell you more about these interactions and any others that may occur with use of Kesimpta. Portions written by Tom Garry, Medical Writer FDA Approves Kesimpta (ofatumumab), Similar to Ocrevus, for Relapsing MS, Aubagio is a registered trademark of Sanofi Genzyme, 2023 The National Multiple Sclerosis Society is a tax exempt 501(c)3 nonprofit organization. The lady in the commercial doesn't even know what to do these medicine ads should be banned and many don't know these prescriptions have side effects these commercials need to be banned from television these prescription ads have gone way too far. She has earned a massive salary from acting on series Insecure where she is cast as a lead in the series. Just administered this morning. It is interesting that Reese Witherspoon did this so early in her career. Uploaded by Pampers on 2019-12-17. Tell your doctor right away if you have any symptoms of infection while using Kesimpta. You'll inject the drug using single-dose syringes or pens. Your doctor can show you how to give yourself Kesimpta injections. Kesimpta is taken once monthly by subcutaneous injection at home, while Ocrevus is taken twice yearly by IV infusion, typically at an IV center. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. Tell your HCP about all the medicines you take, including prescription I can't be sure if Mayzent and Kesimpta in my system as part of the cutover helped or hurt the MS activity. Nov 21, 2022, 2:52 PM UTC alicia keys naked pictures skirt topless funny trivia questions for seniors ken garff ford mizmooz franklin covey weekly planner under armour women shoes Learn about how MS is diagnosed and how treatments differ between these types. You can become a KESIMPTA Connector by calling 1-877-879-0245 Kesimpta is a brand-name prescription medication. By using this site, you agree to the Privacy Policy and Terms of Use. New comments cannot be posted and votes cannot be cast. The best way is to use an FDA-cleared sharps container. until you are ready to use it. It is not known if KESIMPTA will harm your unborn baby. to read it. Official answer: Kami Dimitrova is the actress who appears in the Kesimpta 'Drama' commercial. A biologic is made from parts of living organisms. After that, you can take KESIMPTA at home or wherever you go with a cooler or refrigeration. Yvonne Orji is a Nigerian-American actress who is famous for her role as Molly in the HBO American-comedy drama television series Insecure.. Married, Husband. * For more information about this side effect, see the Side effect focus section below. While only the first week, by day five I felt a positive change in my body that has continued through this morning. You should always consult your doctor or another healthcare professional before taking any medication. She is an actor and comedian based in Los Angeles. Novartis Pharmaceuticals Corporation has updated the Privacy Policy for this website to explain how Age, Height, Parents, Net Wo Judy Fields / Mrs. Darnell / Gabrielle Martin. A boyfriend is thanking his girlfriend's mom for inviting them for a weekend. Credit: No, you're not crazy. Ever since she debuted the character in . You will need to have certain lab tests done before and during Kesimpta treatment. Please talk to your doctor if you experience any reactions. You shouldn't throw away your Sensoready Pen in your household trash. Kesimpta may also cause a rare but serious brain infection called PML. Youll inject Kesimpta into your lower belly, your upper arm, or the front of your thigh. To learn more about treating and managing your condition, sign up to receive Healthlines MS newsletter. an MRI, spinal fluid analysis, and blood tests. Because of the risk for fetal harm, women are cautioned to use birth control during and for 6 months after stopping Kesimpta. 11. Kesimpta is the first B-cell therapy that can be self-administered once monthly at home via the Sensoready autoinjector pen 3. These effects are called interactions. If youre nervous about giving yourself an injection, you may prefer the pen. For more information, see the Pregnancy and breastfeeding with Kesimpta section below. For information about the difference between sex and gender, see this article. Mild infections were very common in clinical trials of Kesimpta, while serious infections were less common. Any required live vaccines should be and active lesions and slowing disability progression. Allyn Rachel. Suave . The approval of Kesimpta is based on results from the Phase III ASCLEPIOS I and II studies, in which Kesimpta demonstrated superiority over Aubagio (oral teriflunomide) in significantly reducing the annualized relapse rate (ARR), three-month confirmed disability progression (CDP), and the number of gadolinium-enhancing (Gd+) T1 and new or enlarging T2 lesions. other federal or state health insurance program. The 20 Most Memorable Women From Commercials The Most Memorable Women Featured On Commercials Greg Stopera Updated December 18, 2019 41.1k votes 9.1k voters 1.8m views Voting Rules Vote up the lovely ladies you remember from ads. Last medically reviewed on January 22, 2023. It's important to keep the KESIMPTA Sensoready Pen The manufacturer of Kesimpta hasnt provided birth control recommendations for males* who use the drug. Individuals with an active hepatitis B virus (HBV) infection should not take Kesimpta. Both the Kesimpta prefilled syringe and the Kesimpta injection pen (known as the SensoReady Pen) contain the same dose of medication. at least 2 weeks before you start treatment with KESIMPTA. Yvonne has an estimated net worth of around more than $500 thousand. Recent vaccination. Dawn Rochelle is an American model, actress and entrepreneur known for her California girl looks and attitude. If you develop an infection during Kesimpta treatment, tell your doctor. She posted on Instagram about her purchasing her first house captioned as, Here is a list of top actresses and their total net worth. Privacy Policy Update: See complete Terms & Conditions at start.kesimpta.com. KESIMPTA can cause serious side effects such as: Infections. Besides talking with your doctor, you can do some research on your own. They work to detect and fight bacteria and viruses in order to help prevent infections. After that, you can move on to 1 dose per month. Typically this type of therapy is only available via infusion at a hospital or infusion center; however, Kesimpta is the first self-administered B-cell therapy for MS. When Does Multiple Sclerosis (MS) Become a Disability? To avoid foaming, do not shake. While there's no cure for MS, there are ways to manage symptoms. Bank of America. Kesimpta is a targeted, precisely dosed and delivered B-cell therapy that has shown superior efficacy with a similar safety profile compared with teriflunomide and is a first-choice treatment option for RMS patients 1. Yes! To learn about other mild side effects, talk with your doctor or pharmacist or read Kesimptas medication guide. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Jane Birkin has asked the French leather goods purveyor to rename the version of the Birkin bag made out of crocodile skin, in protest of crocodile farming and skinning practices . KESIMPTA works by impacting your immune system, What else you know her from Since exploding onto the scene in 2013 as a bubbly AT&T employee named Lily, Vayntrub has become a recognizable actor. This can lead to more frequent or more severe infections. You may have back pain while using Kesimpta. I had increased MS symptoms but they were present before the first injection. If your test is positive for HBV, your doctor may recommend another MS treatment option for you. After ~6 months, one possibly two relapses and new lesions, my Dr and I felt a move was appropriate. If you miss a monthly injection, take it as soon as possible without waiting Your doctor will give you a blood test before starting KESIMPTA to be sure. In Kesimptas clinical trials, people experienced common mild infections. It's called Alongside KESIMPTA, B cells are among immune cells that have been implicated in causing nervous system damage in MS. Another B-cell therapy currently approved to treat MS is Ocrevus. My Dr directed 1 Tylenol and 1 Benadryl for the 3 weekly injections at time of injection to proactively address a high temperature or injection site reaction. Offer not valid under Medicare, Medicaid, or any It's important to keep the KESIMPTA Sensoready Pen between 36 F and 46 F and in its They will also explain how much to take and how often. These trials examined the efficacy and safety of Kesimpta relative to Aubagio in more than 1,800 people with relapsing-remitting MS (RRMS). Injection site reactions were reported in clinical trials of Kesimpta involving people with multiple sclerosis (MS). within 24 hours after your first dose. B cells are among immune cells that have been implicated in causing nervous system damage in MS. Kesimpta is approved by the FDA for the treatment of relapsing forms of multiple sclerosis, to include clinically isolated syndrome . Every individual with RMS may experience a See the detailed Instructions for Use that comes with KESIMPTA for information about how to prepare and inject a KESIMPTA is a flexible, at-home, once-monthly* treatment with proven results for reducing relapses Cyrina Fiallo (born December 29, 1991) is an American actress. Trial participants assigned to the Kesimpta arm of the studies received 20 mg of the monoclonal antibody injected subcutaneously once per month. Talk to your doctor about what birth control method is right for you during this time. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. It can . dose of KESIMPTA and how to properly throw away (dispose of) used KESIMPTA Sensoready pens or prefilled syringes. They can suggest healthy ways to manage weight changes that may happen with MS. Like most drugs, Kesimpta may cause mild or serious side effects. This was one of the most common side effects in studies of the drug. What is relapsing multiple sclerosis (RMS)? They can recommend whether its safe to continue Kesimpta treatment. The differences for both time periods were statistically significant. However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. Multiple sclerosis (MS) can cause neck pain and stiffness. AUBAGIO (teriflunomide). And youll continue using only one injection of Kesimpta each month after that. Call 1-855-KESIMPTA (1-855-537-4678), 8:30 AM8:00 PM ET, MondayFriday. Tell your HCP right away if you have any new or worsening neurologic signs or symptoms. 10 popular commercial actors and where you've seen them before. Mild side effects of Kesimpta that have been reported include: Mild side effects of many drugs may go away within a few days or a couple of weeks. Prescribing information cautions that Kesimpta should not be administered in individuals with active infection, and live or live-attenuated vaccines are not recommended during treatment and after discontinuing treatment until B cells return. . Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. to help us serve relevant health-related advertisements to you about our products or services when you Loading doses are meant to get a high level of the drug into your body. What do we know about the different types of MS? back pain. 2. Both of them are also given as injections under your skin. For general information or to speak with a trained Client Services Specialist, please call MSAAs Helpline at (800) 532-7667, extension 154. here Went from Mayzent on Friday to Kesimpta first weekly dose on Saturday (straight cutover). Other notable television roles have included Elaine Vassal in the Fox legal comedy-drama series Ally McBeal (1997-2002) and Jacqueline White in the Netflix comedy series Unbreakable Kimmy Schmidt (2015-2020). Weakened immune system: Taking KESIMPTA before or after other medicines that weaken your immune system They can help answer any questions you have about side effects from the drug. It is not known if KESIMPTA will harm your unborn baby. Tell your doctor if you're pregnant, With Kesimpta, this means getting more injections during the first month. If you are breastfeeding or considering it, talk with your doctor to learn whether Kesimpta is a safe option for you. Use KESIMPTA exactly as your HCP tells you to use it. Below are answers to a few common questions about Kesimptas dosage. Kesimpta is a fully human antibody, meaning that it was developed from human cells, whereas other (nonhuman) monoclonal antibodies are developed from animal cells. PM ET, MonFri. These infections included: There is also a risk of uncommon, more serious infections during Kesimpta treatment that may require hospitalization. Injection-related reactions are a common side effect of KESIMPTA. They typically go away within a few days. Read on to learn about how Kesimpta is given, as well as its uses, side effects, and more. Injection-related reactions are body-wide reactions that often happen within the first 24 hours after your injection. Heres a short list of some of the mild side effects that Kesimpta can cause. MS, which Kesimpta treats, is a condition that causes your immune system to attack the covering that protects your brain and spinal cord. Relapsing multiple sclerosis is a disease that affects the central nervous system (CNS), If you are considering becoming pregnant or are pregnant, talk with your doctor. In addition to the 40-plus AT&T ads she's . doctor pursues an appeal with your health care plan. whole-body reactions related to Kesimpta injections, such as: low level of certain immunoglobulins (proteins that play a role in your, redness of the skin or deepening of skin color, For example, if you took your missed dose on the 10, flu vaccine thats given as a nasal spray (. In most cases, your doctor will suggest that you avoid non-live vaccines for at least 2 weeks before you start using Kesimpta. Meredith Bishop was born on January 15, 1976 in Los Angeles, California, USA. These reactions may include fever, headache, muscle pain, chills, and Females who can become pregnant Keep in mind these demos do not replace any instructions provided by your doctor. RRMS is the most common form of relapsing MS. What is active secondary progressive multiple sclerosis (SPMS)? Don't let migraines pull you away. Get tailored resources, tips, and more for your specific needs, including information on KESIMPTA. Reactions at or near the injection site include redness However, this side effect wasnt reported in clinical trials. What tests will my doctor need to do before I start on KESIMPTA? to meet your needs. The drug is thought to lessen the activity of your immune system. you can watch an additional demo video or download some quick tips here. Tell your doctor about any recent vaccinations that youve had before you start Kesimpta. Source: usatoday.com. To schedule a demo or to get a Sensoready Training Pen, call 1-855-KESIMPTA They can include: Because an injection-related reaction is most likely to happen with your first injection of Kesimpta, you will receive the first dose at your doctors office or clinic. She also acted in the movie Night School in 2018 and played as Maya which was made on a budget of $29 million and was a massive hit in the box office and was able to collect $103.1 million. the first injections and with later injections. KESIMPTA is a prescribed medical injection which is intended to treat those who suffer from relapsing forms of multiple sclerosis when administered regularly as ordered. The therapy is administered monthly via subcutaneous (under-the-skin) injections and it works by. NPC Privacy Policy. The talented Jevin Smith, plays the father in the ad. Serious side effects may also be possible, though these are rare. Do you want to set these advertising cookies on this browser? If you have an infection, they may stop your Kesimpta treatment until the infection is treated. 1-855-KESIMPTA (1-855-537-4678). Knowing that B-cells are involved with the development of autoimmune diseases, ofatumumab was then studied as a potential treatment for relapsing forms of multiple sclerosis (RMS). If you are pregnant and considering Kesimpta, talk with your doctor about the risks and benefits of this drug. What happens after I'm enrolled in Alongside KESIMPTA? Before taking Kesimpta, be sure to tell your doctor about all medications you take, including prescription and over-the-counter types. Can I receive vaccines while on KESIMPTA? Your doctor will explain how you should inject Kesimpta. Be sure to talk with your doctor about your health history before you start treatment with Kesimpta. Live vaccines contain a weakened form of the bacterium or virus that the vaccine helps prevent an infection from.

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