Still, more research is needed to better understand these findings and pine bark extracts role in reducing damage from head trauma. Regardless, a natural option is available and far worth the wait. Research indicates that Pycnogenol provides an increase in endurance performance of trained athletes. L-arginine is more effective when paired with L-citrulline or pycnogenol to combat erectile dysfunction and improve exercise performance. Additionally, the results showed that the extract has significant anti-pseudomonas activity, making it a potential natural remedy and possible preventive measure for infections. Pine bark extract can help reduce muscle soreness and may help improve conditions relating to poor circulation, high blood pressure, osteoarthritis, diabetes, ADHD, female reproductive issues, skin, erectile dysfunction, eye disease and sports stamina. Studies on human subjects have reported few side effects - even . Pycnogenol (100 mg/day) may reduce hay fever symptoms, according to a clinical trial of 39 people. In one study, 10 patients were treated with placebo and 30 patients were treated with Pycnogenol (100 mg twice or three times daily for two months). ", Mayo Clinic: High blood pressure (hypertension)., Panminerva Medica: "Pycnogenol improvements in asthma management. Circulation and Jet Lag on Long Flights. editor, The Gale Encyclopedia of Alternative Medicine, third edition, 2009. Pycnogenol treatment led to significantly better improvement in the lung function and asthma symptoms. (14, 15). The extract has been widely studied for the past 40 . Arginine is a non-essential amino acid because most humans can make it in their bodies. While the aspirin reduced the risk for cardiovascular disease and colorectal cancer, among other cancers, the risk of gastrointestinal bleeding outweighed those benefits, creating more risks to the body. Can Pycnogenol help? They include: We need more research to know for sure if pycnogenol helps treat these conditions. However, a study of 24 adults with ADHD found that pycnogenol did not improve ADHD symptoms better than placebo. after four weeks of treatment, Pycnogenol-treated patients showed definite evidence of improved in small blood vessel functions and circulation as compared to those not treated. (3), Ototoxicity is ear poisoning and can occur when exposed to certain drugs or chemicals, such as cisplatin, that damage the inner ear or the vestibulocochlear nerve. In a study of 76 people with allergic asthma, Pycnogenol (100 mg/day) added to conventional corticosteroid inhalers for 6 months helped 55% of them reduce inhaler use frequency and dosage. Pycnogenol French maritime pine bark extract acts as a potent blend of antioxidants, it is a natural anti-inflammatory, stimulates generation of collagen and hyaluronic acid and help with natural dilation of blood vessels by supporting production of nitric oxide. Pycnogenol (200 mg/day) may reduce muscle cramps and pain according to a study of 66 healthy people, athletes, and those with venous problems after 4 weeks. Diindolylmethane, or DIM for short, is a plant indolea plant compound with health-promoting properties. Boost gastrointestinal health. Pycnogenol alleviated adverse effects in cancer patients, Pycnogenol improved working memory in older adults, Pycnogenol lowered the use of analgesic drugs in dysmenorrhea (severe menstrual pain), Pycnogenol reduced symptoms in endometriosis comparable to leuprorelin, the standard drug for this condition, Pycnogenol was found to be effective for sun-caused hyperpigmented skin, Pycnogenol reduced the inflammation in lupus patients, Pycnogenol reduced gingival bleeding and plaque formation. In the study, many of the participants on Pycnogenol reduced their dosage of high-blood-pressure medication (nifedipine) [37]. But, as you know, going for the natural approach can make a huge difference in overall health. Note that each number in parentheses [1, 2, 3, etc.] According to a large analysis, Pycnogenol may reduce osteoarthritis symptoms and pain short-term [45, 46]. In a good-quality study, 24 adults aged 24 to 53 years old with attention deficit hyperactivity disorder (ADHD) were given Pycnogenol, placebo, or the standard drug for three weeks. DOI: Scheff SW, et al. A study with four groups of 30 patients each were studied: (1) systemic Pycnogenol and local application; (2) local Pycnogenol only; (3) oral Pycnogenol and (4) medications only (control). ( 1) 2. Pycnogenol is a patented extract of the French maritime pine bark (Pinus pinaster). Eliminate blood clots. Asthma is caused by inflammation in the lungs, which makes it hard to breathe. It also may help regenerate and maintain vitamin C and E levels while also potentially increasing nitric oxide levels, which may relax and protect blood vessels [1]. With time, the participants were able to handle more UV radiation without experiencing skin damage [63]. Berberine is a compound extracted from several plants. These benefits appeared to persist for some time even after stopping supplementation [72]. Staves Off Infections. Pycnogenol has not been found to cause these issues however, it may take a little longer the feel the relief from pain than aspirin. In a study of 20 postmenopausal women, 12 weeks of pycnogenol supplementation improved hydration and elasticity of the skin. Most have similar amounts of active substances and are often sold under the brand name Pycnogenol [6]. Your email address will not be published. Our goal is to not have a single piece of inaccurate information on this website. Pycnogenol can help control blood pressure, which helps improve overall heart health. Research into Pycnogenol has revealed some promising results in over 30 health conditions. It also reduced the size of scars. Here are the many health benefits believed to be possible with Pycnogenol: Reduces "leaky" blood vessels by making the wall proteins (collagen, elastin) more resistant to damage. However, in all the above studies insulin levels did not change. Pycnogenol-treated subjects experienced an improvement in all menopausal symptoms. (2015). The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. Luckily, the Native Americans told them about a tea prepared from the bark of a certain tree, which miraculously led to complete recovery. The review found evidence that pine bark extract may: Similar to its neuroprotective benefits, the metabolic benefits of pine bark extract seem to be related to its antioxidant and anti-inflammatory properties. Our website services, content, and products are for informational purposes only. According to a Japanese study, the combination of Pycnogenolt and L-arginine may produce the results youre looking for, making the bedroom a much happier place. All rights reserved. Pycnogenol (100 mg/day) given to 44 older healthy people with high oxidative stress improved cognitive function, attention, mental performance, and reduced oxidative stress after 12 months [21]. In 19 smokers, increased platelet aggregation was more significantly reduced by 200 mg than either 10 mg or 100 mg of Pycnogenol. Researchers suggest this effect may be due to reduced dopamine and adrenaline levels and increased glutathione levels. A combination supplement (pycnogenol with collagen, coenzyme Q10, and other ingredients) reduced skin aging, elasticity, hydration, and tonicity in a study of 30 women [65]. A Pycnogenol combination product (with l-arginine, alpha lipoic acid, B vitamins, and vitamin K2) may help protect the blood vessels and reduce high homocysteine levels, according to a trial of 25 people [39]. Another clinical trial of 76 people with allergic asthma also suggests that Pycnogenol may reduce IgE antibodies and asthma symptoms [18, 16]. The treatment was four 50 mg capsules of Pycnogenol. However, research on these two groups is limited [71, 15]. Pycnogenol is thought to be an antioxidant that helps protect cells from damage. Researchers from the study suggest that low Pycnogenol dosage and short study duration may explain the lack of benefits [44]. While it may seem intimidating at first, counting macros is a common Erythritol is now one of the most popular natural zero-calorie sweeteners available. Prenatal nutrition can be confusing. According to some researchers, Pycnogenol may lower blood pressure by relaxing blood vessels, reducing free radicals, and lowering inflammation. The effects of the pine bark extract showed significant lower levels of blood glucose and improved endothelial function when compared to placebo, concluding that supplementation of Pycnogenol for . She loves communicating science and empowering people to achieve their optimal health. Potential benefits of folic acid include a reduced risk of cancer, improved cognitive function, stronger bones, enhanced heart health, better pregnancy outcomes and reduced symptoms of restless legs syndrome. For improving exercise capacity in athletes: 200 milligrams daily. It decreased concussion symptoms in 42 student-athletes with a history of sports-related concussions after 6 weeks. Tell your doctor about any supplements you're taking, even if they're natural. A trial of children with ADHD found that Pycnogenol may improve attention, possibly by increasing the total antioxidant status and reducing DNA damage. Your email address will not be published. A clinical trial of 60 health professionals found that Pycnogenol (150 mg/day) may improve cognitive function, attention, mental performance and specific professional skills after 12 weeks. A sitz bath, which involves sitting in warm water for 10 minutes, twice daily, is helpful to patients with anal itching, aching or burning and is known as one of the best ways to get rid of hemorrhoids fast. All rights reserved. PQQ (pyrroloquinoline quinone), also called methoxatin, is a vitamin-like compound that exists naturally in soil and a variety of foods, including spinach, kiwi, soybeans, and human breastmilk . Pain score in the Pycnogenol-treated group was reduced by 56%, as compared to 9.6% reduction in the placebo group. However, healthy people are not immune and can also develop mild infections, in particular after being in improperly chlorinated hot tubs or swimming pools. Sort By. Any medication that you take, including herbal supplements, comes with certain risks. Rating: 100%. Talk to your own doctor about Pycnogenol if youre interested in using it for your own health. Eighty-six patients were treated either with Pycnogenol at 150 mg or 300 mg daily or the drugs diosmin and hesperidin (Daflon)at 1,000 mg daily for two months. It seems to lower blood pressure and improve blood flow to the legs. Too much pressure signals that your heart might be working too hard. One way to add some extra flavor and nutrients to your day is by adding prune juice to your diet. Pine bark extract can make a great addition to your nutritional arsenal for its potent antioxidant support, as well as its added support for blood flow, blood sugar, inflammation, immunity, brain function and skin support. (7). Is Garcinia Cambogia Safe for Weight Loss? chronic anal fissure may take more than 6 weeks to heal. But what are its health benefits? (5). 1. Almost 400 years later, Dr. Jacques Masquelier from France came across Cartiers account and started to look for the active ingredients from the bark of the tree. 4 Items . 10 Ways to Control Blood Sugar without Medication, Pycnogenol (French Maritime Pine Bark Extract): 12 Benefits According to Studies, Reduces leaky blood vessels by making the wall proteins (collagen, elastin) more resistant to damage, Helps maintain high vitamin C and E blood levels for their antioxidant effects, Inhibits platelet aggregation like low-dose aspirin, Reduces hardening in the arteries by increasing nitric oxide production in blood vessels, leading to greater dilatation, Counteracts the damaging effects of ultraviolet radiation, Stimulates the immune system by boosting T and B cell functions, Protects brain cells from toxic chemicals. During week, five without, treatment, reduction of cramps was maintained in all three groups. A study of 32 people with heart failure lasting 12 weeks suggests that a combination of Pycnogenol with CoQ10 (PycnoQ10) may improve blood pressure, heart function, edema, and capacity for physical activity [40]. 1. Information is shared for educational purposes only. In another study, 45 men with ED were given 1.7 grams of L-arginine a day during the first month, 40 mg Pycnogenol twice daily during the second month, and the dose increased to three 40-mg Pycnogenol doses daily during the third month. Vinpocetine is used to increase brain circulation, alertness, cognitive function, concentration, and memory, as well as to lower inflammation and oxidative stress.This article will explore vinpocetine's history, how it works, its potential benefits, and any possible safety issues . You can learn more about how we ensure our content is accurate and current by reading our. There are also several other natural ADHD remedies you can try. There have been a variety of health benefits linked to beta glucan, specifically with the beta-1 3d glucan form which has more biological activity than other types of polysaccharides. In mice, luteolin prevented inflammation and allergic response in the lungs and nose by inhibiting inflammatory cytokines: IL-4, IL-5, and IL-1 3 []. This can cause pain, especially in areas of the body that are used repeatedly, like your hands, fingers, and knees. It may cause side effects such as: Risks. It can also be found as creams, lotions or ointments, typically containing 0.5 percent to 2 percent pine bark extract. Risks. Flavonoids and proanthocyanidins within these fruits can . You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. In 22 German heavy smokers, platelet aggregation was prevented by 500 mg of aspirin or 100 mg Pycnogenol. In oneparticular study published in Research in Pharmaceutical Sciences, researchers investigated the antibacterial activity of pine bark extract essential oil on staph infections, E. coli and pseudomonas infections. Pine bark extract offers some amazing benefits since its so high in powerful antioxidants. Studies have found that nattokinase thins the blood and dissolves accumulated solids in it. Here are 12 benefits of ginkgo biloba. Researchers suggest this benefit may be due to an increase in glutathione and SOD, two antioxidants that may reduce inflammation and oxidative stress in Crohns [76]. The staff there can often answer any questions you have and give you more information about specific brands. This ensures that there is a healthy flow of blood to and from the heart. It also seems to help with cell regeneration and replication. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. All Pycnogenol-treated patients responded favorably in contrast to placebo treatment. A 2015 review indicates that pine bark extract can be used to treat metabolic syndrome and related disorders such as obesity, diabetes, and high blood pressure. A plus sign next to the number [1+, 2+, etc] means that the information is found within the full scientific study rather than the abstract. Infants and children may not be able to synthesize enough of it, but it is present in many protein-rich . Pycnogenol lotions applied postirradiation reduced this immunosuppression to 22% (0.05% Pycnogenol) and 13% (0.1% Pycnogenol). It also appeared to improve their attention span, visual motor skills, and concentration. In another trial, 30 people with type 2 diabetes received a range of pycnogenol doses. Herbal supplements are not regulated by the Food and Drug Administration (FDA), so they may not be up to the same safety standards as medications that have gone through clinical testing and drug trials. From diabetes and sexual function to sports performance and beautiful skin, pine bark extract may be worth exploring to provide results youre looking to achieve. Pycnogenol treatment reduced the need for painkillers by 58% versus one percent in the placebo-treated group. But two months ago, erectile dysfunction health food with the help of the Divine Tool Alliance, the price of all materials related to the puppet mechanism was raised by 20 erectile dysfunction health food 30 , and the price of selling the puppet was reduced by 10. Note that the numbers in parentheses (1, 2, etc.) With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. Pycnogenol reduced foot swelling in 79% of the patients, versus one percent in the placebo group. A randomized, double-blind, placebo-controlled study of 60 patients aged six to 18 years old, was conducted over three months during which patients were randomly assigned to receive either Pycnogenol or placebo. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. You can find out your systolic blood pressure by looking at the top number of a blood pressure test. Study participants took pine bark extract as a supplement, and it was found to be most effective in women who started out with dry skin. If you are thinking of taking Pycnogenol for a serious health condition like asthma or high blood pressure, check with your doctor., People who have autoimmune conditions like multiple sclerosis or lupus should talk to their doctor before trying Pycnogenol. Some pycnogenol supplements are mixed with other antioxidants, such as vitamin C. Pine bark extracts other than pycnogenol are also sold. This nerve affects our balance and hearing by sending signals to the brain. A combination product with Pycnogenol (Lady Prelox) improved sexual function in a clinical trial of 83 healthy postmenopausal women after 8 weeks. In a study of 77 people with symptoms of Irritable Bowel Syndrome (IBS), Pycnogenol (150 mg/day) improved symptoms and reduced the frequency of attacks [77]. 2005-2023 Healthline Media a Red Ventures Company. The active ingredients in pycnogenol can also be extracted from other sources, including peanut skin, grape seed, and witch hazel bark. Thirty patients were treated with 150 mg of Pycnogenol a day and the other 10 patients with placebo for a period of two months. Memorial Sloan-Kettering Cancer Center web site: "About Herbs: Pine Bark Extract. Two studies illustrate the possibilities: One was a randomized, double-blind, placebo-controlled, crossover study in which 26 asthmatic patients were given either a maximum of 200 mg a day of Pycnogenol or placebo for the first period of four weeks and then crossed over to the alternate treatment for the next four weeks.

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